KPH2f is a safe, orally active, and effective dual URAT1/GLUT9 inhibitor with IC 50 s of 0.24 μM and 9.37 μM for URAT1 and GLUT9, respectively. KPH2f shows little effects on OAT1 and ABCG2 (IC 50 =32.14 and 26.74 μM).
Products | Products > Disease Areas > Infection | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Infection | Products > Signaling Pathways > URAT1 | Products > Signaling Pathways > GLUT
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