AChE-IN-6

Overview

AChE-IN-6 (Compound 12a) is an optimal multifunctional ligand with significant inhibition of AChE (EeAChE, IC 50 = 0.20 μM; HuAChE, IC 50 = 37.02 nM) and anti-Aβ activity ( IC 50 = 1.92 μM for self-induced Aβ1-42 aggregation; IC 50 = 1.80 μM for disaggregation of Aβ1-42 fibrils; IC 50 = 2.18 μM for Cu2+-induced Aβ1-42 aggregation; IC 50 = 1.17 μM for disaggregation of Cu2+-induced Aβ1-42 fibrils). AChE-IN-6 has the potential for the research of Alzheimer's disease.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Cholinesterase (ChE)

Product Information

• Catalog No.: HY-144324
• CAS No.: 2758788-95-1
• Molecular Formula: C29H41N5O2
• Molecular Weight: 491.67
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source