HF51116 is a potent antagonist of CXCR4 . HF51116 strongly antagonizes SDF-1α-induced cell migration, calcium mobilization, and CXCR4 internalization. HF51116 inhibits HIV-1 infection via CXCR4 . HF51116 has the potential for the research of HIV-1 infection , hematopoietic stem cell mobilization, and cancer metastasis.
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