ChE/Aβ1-42-IN-1 (compound 28) is a potent ChE and Aβ 1-42 aggregation inhibitor with IC 50 s of 0.062, 0.767 and 1.227 µM for AChE , BuChE and Aβ 1-42 aggregation, respectively. ChE/β1-42-IN-1 shows excellent BBB penetration. ChE/Aβ1-42-IN-1 is a potent multi-targeted anti-Alzheimer's agent.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Cholinesterase (ChE) | Products > Signaling Pathways > Amyloid-β
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