DNMT3A-IN-1

Overview

DNMT3A-IN-1 (compound 1) is an effective and selective DNMT3A inhibitor. DNMT3A-IN-1 exhibits inhibitory activity against DNMT3A, with K I values ranging from 9.16 to 18.85 μM (AdoMet) and 11.37 to 23.34 μM (poly dI-dC). DNMT3A-IN-1 can induce apoptosis in acute myeloid leukemia (AML) cell lines ( Apoptosis ).

Application

Products | Products > Disease Areas > Infection | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Infection | Products > Signaling Pathways > DNA Methyltransferase

Product Information

• Catalog No.: HY-144433
• CAS No.: 1403598-56-0
• Molecular Formula: C30H38N6O4
• Molecular Weight: 546.66
• Purity: 99.94%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (4.57 mM); Clear solution
• Availability: In-stock

Source

Original product source