GAT564

Overview

GAT564 (Compound 15d) is a potent allosteric modulator of cannabinoid 1 receptor ( CB1R ) with EC 50 s of 87 and 320 nM respectively for cAMP and β-arrestin2. GAT564 markedly promotes orthosteric ligand binding to hCB1R. GAT564 is efficacious as a topical agent that significantly reduces intraocular pressure (IOP) in the ocular normotensive murine model of glaucoma.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Cannabinoid Receptor

Product Information

• Catalog No.: HY-144705
• CAS No.: 2851895-01-5
• Molecular Formula: C20H16N2O2S
• Molecular Weight: 348.42
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source