ATX inhibitor 12

Overview

ATX inhibitor 12 (compound 20) is an orally active and potent ATX ( autotaxin ) inhibitor, with an IC 50 of 1.72 nM. ATX inhibitor 12 effectively alleviates lung structural damage with fewer fibrotic lesions at an oral dose of 60 mg/kg in C57Bl/6J mice. ATX inhibitor 12 can be uesd for idiopathic pulmonary fibrosis (IPF) research.

Application

Products | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Others | Products > Signaling Pathways > Phosphodiesterase (PDE)

Product Information

• Catalog No.: HY-144743
• CAS No.: 2771312-16-2
• Molecular Formula: C30H34FN5O2
• Molecular Weight: 515.62
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source