AChE-IN-12

Overview

AChE-IN-12 is a potent and blood-brain barrier (BBB) penetrant acetylcholinesterase ( AChE ) with IC 50 s of 0.41 μM and 1.88 μM for rat AChE and electric eel AChE . AChE-IN-12 is also a good antioxidant (ORAC = 3.3 eq ), selective metal chelator and hu MAO-B inhibitor (IC 50 = 8.8 μM). AChE-IN-12 has remarkable inhibition of self- and Cu 2+ -induced Aβ 1-42 aggregation, as well as exhibits a good neuroprotective effect. AChE-IN-12 can be used for researching Alzheimer’s disease.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Amyloid-β | Products > Signaling Pathways > Cholinesterase (ChE) | Products > Signaling Pathways > Monoamine Oxidase

Product Information

• Catalog No.: HY-144790
• CAS No.: 2764664-52-8
• Molecular Formula: C33H41NO7
• Molecular Weight: 563.68
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source