BMS-604992 (EX-1314) free base is a selective, orally active small-molecule growth hormone secretagogue receptor ( GHSR ) agonist. BMS-604992 free base demonstrates high-affinity binding ( k i =2.3 nM) and potent functional activity ( EC 50 =0.4 nM). BMS-604992 free base can stimulate food intake in rodents.
Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > GHSR
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