Dynole 2−24

Overview

Dynole 2−24 is an indole-based dynamin GTPase inhibitor ( IC 50 =0.56 μM for dynamin I). Dynole 2−24 is nontoxic and shows increased potency against dynamin I and II in vitro and in cells (IC ₅₀(CME) =1.9 μM). Dynole 2−24 also shows 4.4-fold selectivity for dynamin I. Dynole 2−24 is active in-cell inhibitor of clathrin-mediated endocytosis. CME: Clathrin mediated endocytosis

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Cytoskeleton | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Dynamin

Product Information

• Catalog No.: HY-145080
• CAS No.: 1416313-72-8
• Molecular Formula: C24H41N3
• Molecular Weight: 371.60
• Purity: 99.07%
• Storage: Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source