JNJ-27390467

Overview

JNJ-27390467 is a potent, orally active, and selective tryptase inhibitor ( human β-tryptase IC 50 = 3.6 nM, K i = 3.7 nM). JNJ-27390467 exhibits excellent selectivity over trypsin of ~5000-fold. JNJ-27390467 shows effects in animal models of airway inflammation. JNJ-27390467 can be used for allergic asthma research.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Allergy | Products > Disease Areas > Allergic Asthma | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Ser/Thr Protease

Product Information

• Catalog No.: HY-14515
• CAS No.: 1025795-12-3
• Molecular Formula: C33H30N2O5
• Molecular Weight: 534.60
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source