RTICBM-189

Overview

RTICBM-189 is a potent, brain-penetrant allosteric modulator of the cannabinoid type-1 (CB 1 ) receptor with a pIC 50 of 7.54 in Ca 2+ mobilization assay. RTICBM-189 has pIC 50 s of 5.29 and 6.25 for hCB 1 and mCB 1 , respectively. RTICBM-189 significantly and selectively attenuates the reinstatement of the addictive agent-seeking behavior in rats.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Pain | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Cannabinoid Receptor

Product Information

• Catalog No.: HY-145196
• CAS No.: 551909-15-0
• Molecular Formula: C15H14Cl2N2O
• Molecular Weight: 309.19
• Purity: 99.73%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 2.5 mg/mL (8.09 mM); Clear solution
• Availability: In-stock

Source

Original product source