APJ receptor agonist 4

Overview

APJ receptor agonist 4 is a potent and orally active agonist of apelin receptor ( APJ ) with EC 50 and Ki of 0.06 nM and 0.07 nM respectively. APJ receptor agonist 4 displays excellent pharmacokinetic profiles in the rodent heart failure (HF) model. APJ receptor agonist 4 also shows an acceptable safety profile in preclinical toxicology studies. APJ receptor agonist 4 leads to improved cardiac function and can be used for researching the HF disease.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Apelin Receptor (APJ)

Product Information

• Catalog No.: HY-145284
• CAS No.: 2762567-70-2
• Molecular Formula: C28H28ClFN6O3
• Molecular Weight: 551.01
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source