APJ receptor agonist 5

Overview

APJ receptor agonist 5 (compound 3) is a potent and orally active agonist of apelin receptor ( APJ ) with an EC 50 of 0.4 nM. APJ receptor agonist 5 displays excellent pharmacokinetic profiles in the rodent heart failure (HF) model. APJ receptor agonist 5 also shows an acceptable safety profile in preclinical toxicology studies. APJ receptor agonist 5 leads to improved cardiac function and can be used for researching the HF disease.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Apelin Receptor (APJ)

Product Information

• Catalog No.: HY-145285
• CAS No.: 2135514-20-2
• Molecular Formula: C26H29N3O6
• Molecular Weight: 479.52
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source