IMPDH2-IN-2 is a potent inhibitor of inosine 5’-monophosphate dehydrogenase ( IMPDH ) with a K i,app value of 14 μM, respectively. IMPDH2-IN-2 displays moderate antibacterial activity (MIC = 6.3 and 11 μM in minimal GAST/Fe and rich 7H9/ADC/Tween media, respectively). IMPDH2-IN-2 is a potential anti-tuberculosis agent.
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