S-MGB-234 is a minor groove binder of Animal African Trypanosomiasis (AAT). S-MGB-234 displays excellent in vitro activities against the principal causative organisms of AAT; Trypanosoma congolense , and Trypanosoma vivax . S-MGB-234 does not show cross-resistance with the current diamidine agents and are not internalized via the transporters used by diamidines.
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