BMS-986143 is an orally active, reversible BTK inhibitor with an IC 50 of 0.26 nM. BMS-986143 also inhibits TEC, BLK , BMX, TXK FGR, YES1, ITK with IC 50 s of 3 nM, 5 nM, 7 nM, 10 nM, 15 nM,19 nM, 21 nM, respectively. BMS-986143 can be used for the research of autoimmune diseases.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Btk
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