Clozapine hydrochloride

Overview

Clozapine hydrochloride (HF 1854 hydrochloride) is an antipsychotic used for the research of schizophrenia. Clozapine hydrochloride has high affinity for a number of neuroreceptors. Clozapine hydrochloride is a potent antagonist of dopamine D2 with a K i of 75 nM. Clozapine hydrochloride inhibits the muscarinic M1 receptor and serotonin 5HT2A receptor with K i s of 9.5 nM and 4 nM, respectively. Clozapine hydrochloride is also a potent and selective agonist at the muscarinic M4 receptor ( EC 50 =11 nM).

Application

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Product Information

• Catalog No.: HY-14539A
• CAS No.: 54241-01-9
• Molecular Formula: C18H20Cl2N4
• Molecular Weight: 363.28
• Purity: 99.83%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (6.88 mM); Clear solution
• Availability: In-stock

Source

Original product source