8-Azanebularine

Overview

8-Azanebularine, a compound with hydrogen in place of the C6 amino group, inhibits the ADAR2 reaction at high concentrations ( IC 50 =15 mM). 8-Azanebularine is incorporated into an RNA structure recognized by human ADAR2 results in high-affinity binding ( K D =2 nM). 8-Azanebularine can be used for the research of ADAR-catalyzed RNA-editing reaction.

Application

Products | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Others | Products > Signaling Pathways > Adenosine Deaminase

Product Information

• Catalog No.: HY-145442
• CAS No.: 38874-46-3
• Molecular Formula: C9H11N5O4
• Molecular Weight: 253.21
• Purity: 99.33%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 1.25 mg/mL (4.94 mM); Clear solution
• Availability: In-stock

Source

Original product source