Linaprazan glurate

Overview

Linaprazan glurate (X842) is an orally atcive prodrug of Linaprazan ( HY-100412 ) with a potent and prolonged inhibitory effect on gastric acid secretion. Linaprazan glurate is rapidly transformed by enzymatic cleavage into its active metabolite, linaprazan. Linaprazan glurate is a potassium-competitive acid blocker. Linaprazan glurate selectively inhibites acid formation from gastric H⁺/K⁺-ATPase in a potassium-dependent manner ( IC 50 = 436.2 nM). Linaprazan glurate can be used for the studies of erosive esophagitis (EE).

Application

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Product Information

• Catalog No.: HY-145578
• CAS No.: 1228559-81-6
• Molecular Formula: C26H32N4O5
• Molecular Weight: 480.56
• Purity: 99.65%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 1.25 mg/mL (2.60 mM); Clear solution
• Availability: In-stock

Source

Original product source