Onradivir

Overview

Onradivir (ZSP1273) is an orally active antiviral agent targeting influenza A virus RNA polymerase PB2 subunit with an IC 50 of 0.562 nM. Onradivir inhibits cap binding to influenza A virus RNA polymerase PB2 subunit, suppresses viral replication, reduces viral titres and RNA loads, and inhibits influenza A virus infection . Onradivir maintains high survival rates in influenza A virus-infected mice, and reduces influenza A virus titers in a murine model . Onradivir can be used for the research of influenza A virus infection .

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Viral Infection | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Infection | Products > Signaling Pathways > Influenza Virus | Products > Signaling Pathways > DNA/RNA Synthesis

Product Information

• Catalog No.: HY-145586
• CAS No.: 2200336-20-3
• Molecular Formula: C22H22F2N6O2
• Molecular Weight: 440.45
• Purity: 99.53%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: 2.5 mg/mL (5.68 mM); Clear solution; Need ultrasonic
• Availability: In-stock

Source

Original product source