DIF-3

Overview

DIF-3 is an orally active anticancer agent. DIF-3 reduces the expression levels of cyclin D1 and c-Myc by facilitating their degradation via activation of GSK-3β . DIF-3 inhibits Wnt/β-catenin signaling pathway-related proteins in cells. DIF-3 induces reactive oxygen species (ROS) and autophagy . DIF suppresses the growth of Trypanosoma . cruzi in HT1080 cells. DIF-3 exerts antitumor effects both in vitro and in vivo.

Application

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Product Information

• Catalog No.: HY-145669
• CAS No.: 113411-17-9
• Molecular Formula: C13H17ClO4
• Molecular Weight: 272.72
• Purity: 99.84%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 2.5 mg/mL (9.17 mM); Clear solution
• Availability: In-stock

Source

Original product source