GPR84 antagonist 2

Overview

GPR84 antagonist 2 (compound 33) is a potent, selective, and orally active GPR84 antagonist ( IC 50 =8.95 nM). GPR84 antagonist 2 shows improved potency in the calcium mobilization assay and the ability to inhibit the chemotaxis of neutrophils and macrophages upon GPR84 activation. GPR84 antagonist 2 has the potential for the research of ulcerative colitis.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > GPR84

Product Information

• Catalog No.: HY-145697
• CAS No.: 2244269-74-5
• Molecular Formula: C28H16Cl2NaO4PS2
• Molecular Weight: 605.42
• Purity: 99.06%
• Storage: -20°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Availability: In-stock

Source

Original product source