AAK1-IN-5 is a highly selective, CNS-penetrable, and orally active adaptor protein-2-associated kinase 1 ( AAK1 ) inhibitor ( AAK1 IC 50 of 1.2 nM, Filt K i of 0.05 nM, and cell IC 50 of 0.5 nM). AAK1-IN-4 has the potential for the research for neuropathic pain.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > AAK1
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