Lopinavir

Overview

Lopinavir (ABT-378) is a highly potent, selective peptidomimetic inhibitor of the HIV-1 protease , with K i s of 1.3 to 3.6 pM for wild-type and mutant HIV protease . Lopinavir acts by arresting maturation of HIV-1 thereby blocking its infectivity. Lopinavir is also a SARS-CoV 3CL pro inhibitor with an IC 50 of 14.2 μM.

Application

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Product Information

• Catalog No.: HY-14588
• CAS No.: 192725-17-0
• Molecular Formula: C37H48N4O5
• Molecular Weight: 628.80
• Purity: 99.71%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 1 year , -20°C, 6 months
• Solubility: ≥ 25 mg/mL (39.76 mM); Clear solution
• Availability: In-stock

Source

Original product source