Lopinavir-d 8

Overview

Lopinavir-d 8 (ABT-378-d 8 ) is the deuterium labeled Lopinavir. Lopinavir (ABT-378) is a highly potent, selective peptidomimetic inhibitor of the HIV-1 protease, with K i s of 1.3 to 3.6 pM for wild-type and mutant HIV protease . Lopinavir acts by arresting maturation of HIV-1 thereby blocking its infectivity. Lopinavir is also a SARS-CoV 3CLpro inhibitor with an IC 50 of 14.2 μM.

Application

Products | Products > Signaling Pathways > Others | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Infection | Products > Signaling Pathways > Isotope-Labeled Compounds | Products > Signaling Pathways > HIV | Products > Signaling Pathways > HIV Protease | Products > Signaling Pathways > SARS-CoV

Product Information

• Catalog No.: HY-14588S1
• CAS No.: 1224729-35-4
• Molecular Formula: C37H40D8N4O5
• Molecular Weight: 636.85
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source