CC214-2

Overview

CC214-2 is an oral active and selective mTOR kinase inhibitor. CC214-2 targets to both of mTORC1 (pS6) and mTORC2 (pAktS473). CC214-2 induces autophagy , which is a potential target for host-directed therapy (HDT) in tuberculosis. CC214-2 exhibits synergistic bactericidal and sterilizing activity agasinst tuberculosis (TB), and shortens the treatment duration. CC214-2 also inhibits Rapamycin ( HY-10219 )-resistant signaling and the growth of glioblastomas in vitro and in vivo.

Application

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Product Information

• Catalog No.: HY-145931
• CAS No.: 1228012-18-7
• Molecular Formula: C20H25N5O3
• Molecular Weight: 383.44
• Purity: 98.41%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source