BJJF078 is an aminopiperidine derivative. BJJF078 is a potent inhibitor of recombinant human and mouse Transglutaminase enzyme ( TG2 ) activity, IC 50 values of 41 and 54 nM, respectively. BJJF078 also inhibits the close related enzyme TG1 , with an IC 50 of 0.16 μM. BJJF078 can be used for Multiple sclerosis (MS) research.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Glutaminase
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