HIV-1 inhibitor-25

Overview

HIV-1 inhibitor-25 (compound R-12a) is a highly potent HIV-1 reverse transcriptase , with an IC 50 value of 0.1061 μM. HIV-1 inhibitor-25 has high antiretroviral activity against WT HIV-1 with an EC 50 of 13.6 nM, and exhibits relatively low cytotoxicity with a CC 50 of 33.13 μM in MT-4 cells. HIV-1 inhibitor-25 also has inhibitory activity against HIV-1 mutant strains (L100I, K103N, Y181C, Y188L, E138K, F227L+V106A) with EC 50 of 0.1961 ~ 5.8136 μM. HIV-1 inhibitor-25 can be used for researching AIDS.

Application

Products | Products > Disease Areas > Infection | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > HIV

Product Information

• Catalog No.: HY-146019A
• CAS No.: 2475658-74-1
• Molecular Formula: C26H19N5O2
• Molecular Weight: 433.46
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source