AChE-IN-14

Overview

AChE-IN-14 (compound 5) is a potent cholinesterase inhibitor with IC 50 s of 0.46 , 0.48, and 0.44 μM for electric eel acetylcholinesterase ( eeAChE ), human recombinant acetylcholinesterase ( hAChE ), and equine serum butyrylcholinesterase ( eqBuChE ), respectively. AChE-IN-14 exhibits high affinity toward human H 3 receptor (H 3 R; K i = 159.8 nM). AChE-IN-14 can be used for the research of Alzheimer’s disease.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Cholinesterase (ChE) | Products > Signaling Pathways > Histamine Receptor

Product Information

• Catalog No.: HY-146035
• CAS No.: 2390042-05-2
• Molecular Formula: C28H35NO3
• Molecular Weight: 433.58
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source