RSV-IN-5 (Compound 4) is a potent dual inhibitor of wild-type and mutant respiratory syncytial virus ( RSV ) fusion proteins. RSV-IN-5 exhibits potent anti-RSV activities against not only wild-type A2 F protein (EC 50 =2.0 nM), but also D486N-mutant F protein (EC 50 =8.1 nM).
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