γ-Secretase modulator 12

Overview

γ-Secretase modulator 12 (Compound 1a) is a γ-secretase modulator that can selectively decrease amyloid-β42 (Aβ42) levels ( IC 50 of 0.39 µM). γ-Secretase modulator 12 can be used for Alzheimer’s disease research . γ-Secretase modulator 12 has a good brain/plasma ratio (Kp, brain = 0.72) in mice.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Stem Cell/Wnt | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > γ-secretase | Products > Signaling Pathways > Amyloid-β

Product Information

• Catalog No.: HY-146151
• CAS No.: 2204249-82-9
• Molecular Formula: C25H23N3O2
• Molecular Weight: 397.47
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source