CCT373566

Overview

CCT373566 is a potent and orally active molecular glue degrader of transcriptional repressor BCL6 , with an IC 50 of 2.2 nM. CCT373566 shows strong antiproliferative efficacy in vitro and reduction in tumor growth in vivo.

Application

Products | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Molecular Glues | Products > Signaling Pathways > Bcl-2 Family

Product Information

• Catalog No.: HY-146185
• CAS No.: 2378853-66-6
• Molecular Formula: C26H29ClF2N6O3
• Molecular Weight: 547.00
• Purity: 99.61%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 2.5 mg/mL (4.57 mM); Clear solution
• Availability: In-stock

Source

Original product source