PDE4B/7A-IN-1

Overview

PDE4B/7A-IN-1 is a dual PDE4B/PDE7A inhibitor. PDE4B/7A-IN-1 shows IC 50 values of 69.0 μM for PDE4B and 57.0 μM for PDE7A, as well as K i values of 539 nM for 5-HT 1A and 328 nM for 5-HT 7 . PDE4B/7A-IN-1 shows favorable membrane permeability. PDE4B/7A-IN-1 can be used for the study of cognitive impairment and depression.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Depression | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Phosphodiesterase (PDE) | Products > Signaling Pathways > 5-HT Receptor

Product Information

• Catalog No.: HY-146201
• CAS No.: 2511632-25-8
• Molecular Formula: C25H35N3O3
• Molecular Weight: 425.56
• Purity: 99.63%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source