COX-2/5-LOX-IN-1

Overview

COX-2/5-LOX-IN-1 (compound 3a) is a potent and dual inhibitor of COX-2 / 5-LOX . COX-2/5-LOX-IN-1 is a benzothiophen-2-yl pyrazole carboxylic acid derivative. COX-2/5-LOX-IN-1 shows the most potent analgesic and anti-inflammatory activities surpassing that of Celecoxib and Indomethacin. COX-2/5-LOX-IN-1 shows potent COX-1 , COX-2 and 5-LOX inhibitory activity with IC 50 s of 12.13, 0.4 and 4.96 μM, respectively.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > COX

Product Information

• Catalog No.: HY-146294
• CAS No.: 2410384-50-6
• Molecular Formula: C14H10ClN3O4S2
• Molecular Weight: 383.83
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source