HD-TAC7

Overview

HD-TAC7 is a potent PROTAC HDAC degrader with IC 50 values of 3.6 μM, 4.2 μM and 1.1 μM for HDAC1 , HDAC2 and HDAC3 , respectively. HD-TAC7 can decreases NF-κB p65 in RAW 264.7 macrophages. HD-TAC7 can be used for the research of inflammatory diseases like asthma and chronic obstructive pulmonary disease (COPD).

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > HDAC

Product Information

• Catalog No.: HY-146346
• CAS No.: 2978763-95-8
• Molecular Formula: C33H32FN7O7
• Molecular Weight: 657.65
• Purity: 98.53%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.63 mg/mL (4.00 mM); Clear solution
• Availability: In-stock

Source

Original product source