Keap1-Nrf2-IN-8

Overview

Keap1-Nrf2-IN-8 (compound 12d) is a potent Keap1-Nrf2 PPI ( Keap1-Nrf2 protein−protein interaction) inhibitor with IC 50 s of 64.5 nM and 14.2 nM for FP and TR-FRET assays, respectively. Keap1-Nrf2-IN-8 significantly increases the mRNA levels of Nrf2 downstream genes, GSTM3, HMOX2 and NQO1.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > NF-κB | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Keap1-Nrf2

Product Information

• Catalog No.: HY-146578
• CAS No.: 2769963-54-2
• Molecular Formula: C35H31FN2O9S2
• Molecular Weight: 706.76
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source