Thalidomide

Overview

Thalidomide inhibits cereblon (CRBN), a part of the cullin-4 E3 ubiquitin ligase complex CUL4-RBX1-DDB1, with a K d of ∼250 nM, and has immunomodulatory, anti-inflammatory and anti-angiogenic cancer properties. Thalidomide can work as molecular glue to potentiate substrate.

Application

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Product Information

• Catalog No.: HY-14658
• CAS No.: 50-35-1
• Molecular Formula: C13H10N2O4
• Molecular Weight: 258.23
• Purity: 99.98%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 1 year , -20°C, 6 months
• Solubility: ≥ 2.5 mg/mL (9.68 mM); Clear solution
• Availability: In-stock

Source

Original product source