HDAC6-IN-5

Overview

HDAC6-IN-5 (compound 11b) is a potent and BBB-penetrated HDAC6 inhibitor, with an IC 50 of 0.025 μM. HDAC6-IN-5 exhibits strong inhibitory activity against Aβ 1-42 self-aggregation and AChE , with IC 50 values of 3.0 and 0.72 μM. HDAC6-IN-5 can enhance neurite outgrowth without significant neurotoxicity.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > HDAC | Products > Signaling Pathways > Amyloid-β | Products > Signaling Pathways > Cholinesterase (ChE)

Product Information

• Catalog No.: HY-146678
• CAS No.: 2413603-15-1
• Molecular Formula: C20H14BrN3O2
• Molecular Weight: 408.25
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source