Zenidolol (Standard)

Overview

Zenidolol (ICI-118551) (Standard) is the analytical standard of Zenidolol ( HY-100543 ). This product is intended for research and analytical applications. Zenidolol is a selective β2-adrenergic receptor antagonist with K i values of Zenidolol for β2, β1 and β3 adrenergic receptors of 0.7, 49.5 and 611 nM, respectively. Zenidolol exerts antitumor effects via inducing apoptosis , inhibiting tumor sphere formation, and downregulating the HIF pathway by blocking β2-AR on tumor cells. Zenidolol exhibits a unique pulmonary vessel-specific vasodilatory effect in mouse models. Zenidolol can be used as an intraocular pressure-lowering agent in ophthalmic disease research .

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Cancer | Products > Disease Areas > Visual System Disease | Products > Disease Areas > Cardiovascular Disease | Products > Disease Areas > Ocular Hypertension | Products > Disease Areas > Hypertension | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Others | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Neurological Disease | Products > Research Areas > Cardiovascular Disease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Caspase | Products > Signaling Pathways > Bcl-2 Family | Products > Signaling Pathways > HIF/HIF Prolyl-Hydroxylase | Products > Signaling Pathways > Adrenergic Receptor | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-100543R
• CAS No.: 72795-26-7
• Molecular Formula: C17H27NO2
• Molecular Weight: 277.40
• Purity: 95%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source