PDE4-IN-9

Overview

PDE4-IN-9 (Compound 5j) is a potent inhibitor of PDE4 . PDE4-IN-9 exhibits lower IC 50 value (1.4 μM) against PDE4 than parent rolipram (2.0 μM) in in vitro enzyme assay. PDE4-IN-9 also displays good in vivo activity in animal models of asthma/COPD and sepsis induced by LPS.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Phosphodiesterase (PDE)

Product Information

• Catalog No.: HY-146974
• CAS No.: 2519450-32-7
• Molecular Formula: C15H12N4O3S
• Molecular Weight: 328.35
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source