DNA Gyrase-IN-1 (compound 42) is a potent and selective DNA gyrase inhibitor with an IC 50 value of 2.6 µM. DNA Gyrase-IN-1 has high inhibitory activity against Mycobacterium tuberculosis ( Mtb ) with MIC of 0.49 µM. DNA Gyrase-IN-1 can be used for researching tuberculosis.
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