PY109

Overview

PY109 is an orally active and highly selective aryl hydrocarbon receptor ( AHR ) agonist. PY109's EC 50 values in human-derived HepG2 and mouse Hepa-1c1c7 cells are 1.2 nM and 1.4 nM respectively. PY109 significantly upregulates the expression of CYP1A1 and IL-22 , and inhibits the expression of IL-17A . PY109 significantly improves colitis in mice. PY109 can be used for research on colitis.

Application

Products | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Aryl Hydrocarbon Receptor | Products > Signaling Pathways > Cytochrome P450 | Products > Signaling Pathways > Interleukin Related

Product Information

• Catalog No.: HY-147128
• CAS No.: 2378039-23-5
• Molecular Formula: C15H9F3N2O
• Molecular Weight: 290.24
• Purity: 99.15%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source