SAE-14

Overview

SAE-14 (compound SAE-14) is a potent, specific GPR183 antagonist with an IC 50 value of 28.5 nM, can antagonize 7α, 25-OHC–induced calcium mobilization with IC 50 value below 50 nM in HL-60 cells. GPR183 antagonist-1 can reverse allodynia in mice.

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Viral Infection | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Neurological Disease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > EBI2/GPR183

Product Information

• Catalog No.: HY-147222
• CAS No.: 1241280-25-0
• Molecular Formula: C19H19F3N2O2
• Molecular Weight: 364.36
• Purity: 98.60%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source