SJ1008030

Overview

SJ1008030 (compound 8) is a JAK2 PROTAC which selectively degrades JAK2 . SJ1008030 inhibits MHH–CALL-4 cell growth with an IC 50 of 5.4 nM. SJ1008030 can be used for the research of leukemia. (Pink: JAK2 ligand ( HY-15315 ); Blue: Cereblon ligand ( HY-W834174 ); Black: linker).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > JAK/STAT Signaling | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Stem Cell/Wnt | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > JAK

Product Information

• Catalog No.: HY-147330
• CAS No.: 2863634-96-0
• Molecular Formula: C42H43N13O7S
• Molecular Weight: 873.94
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source