SJ1008030 TFA

Overview

SJ1008030 (compound 8) TFA is a JAK2 PROTAC which selectively degrades JAK2 . SJ1008030 TFA inhibits MHH–CALL-4 cell growth with an IC 50 of 5.4 nM. SJ1008030 TFA can be used for the research of leukemia. (Pink: JAK2 ligand ( HY-15315 ); Blue: Cereblon ligand ( HY-W834174 ); Black: linker).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > JAK/STAT Signaling | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Stem Cell/Wnt | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > JAK

Product Information

• Catalog No.: HY-147330A
• CAS No.: 2863634-97-1
• Molecular Formula: C44H44F3N13O9S
• Molecular Weight: 987.96
• Purity: 98.12%
• Storage: -20°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Availability: In-stock

Source

Original product source