NFATc1-IN-1 (compound A04) is a potent inhibitor of RANKL-induced osteoclast formation, with an IC 50 of 1.57 μM. NFATc1-IN-1 shows anti-osteoclastogenic effects through reducing the RANKL-induced nuclear translocation of NFATc1 . NFATc1-IN-1 can be used for osteoclastic diseases research.
Products | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Others | Products > Signaling Pathways > Nuclear Factor of activated T Cells (NFAT)
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