Rolapitant

Overview

Rolapitant (SCH619734) is a potent, selective, long-acting and orally active neurokinin 1 (NK1) receptor antagonist with a K i of 0.66 nM. Rolapitant does not interact with CYP3A4 . Rolapitant shows potent anti-emetic activity in a ferret emesis model.

Application

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Product Information

• Catalog No.: HY-14751
• CAS No.: 552292-08-7
• Molecular Formula: C25H26F6N2O2
• Molecular Weight: 500.48
• Purity: 99.89%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (5.00 mM); Clear solution
• Availability: In-stock

Source

Original product source