Totrombopag

Overview

Totrombopag is an orally effective thrombopoietin receptor ( TpoR ) agonist. By activating TpoR , Totrombopag initiates an intracellular signaling cascade mediated by JAK2 kinase and the transcription factor Stat5 , a signaling process that is the primary mechanism regulating megakaryocyte growth and differentiation into platelets. Totrombopag can be used to study platelet production and megakaryocyte biology.

Application

Products | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Others | Products > Signaling Pathways > Thrombopoietin Receptor

Product Information

• Catalog No.: HY-14756
• CAS No.: 376592-42-6
• Molecular Formula: C25H22N8O2
• Molecular Weight: 466.49
• Purity: 99.00%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source