JMI-105

Overview

JMI-105 is a potent PfFP-2 ( Plasmodium falciparum falcipain-2 protease) inhibitor. JMI-105 inhibits the growth of CQ S (3D7; IC 50 =8.8 µM) and CQ R (RKL-9; IC 50 =14.3 µM) strains of P. falciparum . JMI-105 significantly decreases parasitemia and prolonged host survival in a murine model with P. berghei ANKA infection . JMI-105 has the potential to be used as an anti-malarial agent.

Application

Products | Products > Disease Areas > Infection | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > Parasite

Product Information

• Catalog No.: HY-147849
• CAS No.: 2227315-30-0
• Molecular Formula: C20H23N3O2
• Molecular Weight: 337.42
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source